Health Ministry approves new treatment regimen for multidrug-resistant TB in india

The new BPaLM regimen consisting of four drugs — Bedaquiline, Pretomanid, Linezolid and Moxifloxacin — has proven to be a safe, more effective and quicker treatment option than previous procedures, the Ministry says.
This move by the Union Government is expected to significantly boost the country’s progress to achieve its national goal of Ending TB in India


The BPaLM regimen, which consists four-drug combination – Bedaquiline, Pretomanid, Linezolid and Moxifloxacin, has been proven to be safe, more effective and a quicker treatment option than the previous MDR-TB treatment procedure. While traditional MDR-TB treatments can last up to 20 months with severe side effects, BPaLM regimen can cure the drug-resistant TB in just six months with high treatment success rate. India’s 75,000 drug-resistant TB patients will now be able to avail benefit of this shorter regimen. With the other advantages, there will be an overall saving in cost.

Department of Health & Family Welfare, in consultation with Department of Health Research ensured validation of this new TB treatment regimen that witnessed a thorough review of evidences by in-country subject experts. Department of Health & Family Welfare has also got a Health Technology Assessment done through the Department of Health Research to ensure that this MDR-TB treatment option is safe and cost effective.  

This move by Government of India is expected to significantly boost the country’s progress to achieve its national goal of Ending TB. A country-wide time-bound roll out plan of the BPaLM regimen is being prepared by the Central TB Division of Ministry of Health & Family Welfare in consultation with States/UTs, which includes rigorous capacity building of health professionals for safe administration of the new regimen.

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